Wenfei Zhang

College of Life Sciences, Hainan Normal University, Haikou, 570100, Hainan, China
Author    Correspondence author
Bt Research, 2024, Vol. 15, No. 1   doi: 10.5376/bt.2024.15.0003
Received: 15 Nov., 2023    Accepted: 30 Dec., 2023    Published: 26 Jan., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Zhang W.F., 2024, Comparative genomic analysis of Bacillus thuringiensis strains for uncovering evolutionary mechanisms, Bt Research, 15(1): 20-29 (doi: 10.5376/bt.2024.15.0003)

Bacillus thuringiensis (Bt), widely used as a biopesticide, exhibits significant genetic variability, which is crucial for its adaptability and functional capabilities. This study outlines the general characteristics, biological functions, and applications of Bt strains, emphasizing the importance of genetic diversity. Utilizing advanced genomic sequencing technologies and bioinformatics tools, the study analyzes the core and pan-genome compositions, and explores the genetic essence of highly virulent and novel Bt strains through case studies, providing insights into their evolutionary trajectories. The comprehensive genomic approach not only advances our understanding of microbial biodiversity and evolution but also enhances the role of comparative genomics in fostering biotechnological innovations. This research, through comparative genomic analysis of different Bacillus thuringiensis (Bt) strains, aims to reveal their genetic foundations and evolutionary mechanisms, providing a scientific basis for developing more effective biopesticide strategies and supporting theoretical advancements in biotechnological innovation.

Bacillus thuringiensis; Comparative genomics; Evolutionary mechanisms; Biopesticides; Genetic diversity